Cheap amoebic dysentery drug 'promising' - BBC News

It showed that auranofin was much better than the current treatment, metronidazole, at killing Entamoeba histolytica. Follow-up experiments showed that it was also more effective at treating mice and hamsters which had been infected with the ameoba.

A New Way to Kill Amoebas, From An Old Drug - Corante

They did have a good positive control, though - the nitroimidazole drug metronidazole, which is the only agent approved currently against the parasite (and to which it's becoming resistant). A screen of nearly a thousand known drugs and ...

Cheap arthritis drug effective against killer amoebic parasites that infect 50 million a year - New York Daily News

The experiments suggest auranofin would be 10 times more effective than metronidazole, the current medication for amoebic infection, which means that it could be used in very small doses or even as a one-off tablet. Better still, the drug has ...

Arthritis drug could also help combat major cause of dysenteric death worldwide - Newstrack India

It is listed by the National Institutes of Health as a category B priority biodefense pathogen. Current treatment relies on metronidazole, which has adverse effects, and potential resistance to the drug is an increasing concern. "Because ...

They May Look Alike, But Treat Parasites Differently: Doctor - Voice of America

Amebiasis can be treated with metronidazole for colitis or liver abscesses, or with iodoquinol, paromomycin and diloxanide for asymptomatic carries, he said. Other parasites (and their cures ) include: giardiasis (metronidazole, nitazoxanide or paromomycin ...

Gold-Containing Arthritis Drug Shows Promise for Treating Major Intestinal Infection Caused by Parasite - Healthcanal.com

An antibiotic called metronidazole is currently the treatment of choice for amebiasis. However, metronidazole is associated with both undesirable side effects and an increasing concern for drug resistance. In this study, researchers from the ...

Dysentery May Be Treatable With Cheap Arthritis Drug - Medical News Today

Using a high-throughput drug screen he and his colleagues found that auranofin was 10 times more potent against the parasite Entamoeba histolytica than the current treatment metronidazole. They said their study illustrates the importance of ...

Another drug found defective - DAWN Group

Prof Jamal gave the generic name of the drug as metronidazole and said a lowest bidder was supplying the drug with the locally  registered Macronid. A medical expert at Pims said metronidazole drug is used to treat trichomoniasis, a sexually ...

RA drug effective against Entamoeba histolytica - News-Medical.Net

"In our studies in animal models, auranofin was ten times more potent against this parasite than metronidazole." In a mouse model of amebic colitis and a hamster model of amebic liver abscess, the drug markedly decreased the number of parasites ...